Highly Recommended 20+ Best Isekai Anime With OP MC 2021

Isekai anime with op mc
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Isekai anime, this genre is quite known around in the anime as well as the manga in the current years.

It’s a genre that has been seen raising the main character theme from the original world to quite a different one.

This anime is quite notorious for the Isekai anime with op mc who are notably protagonists.

But in the past few years, anime lovers might have seen a lot of overpowered characters in the supporting role.

So, it can get weird to watch the show wherein the protagonist can easily defeat the opponent by a simple finger lift, but it’s Isekai’s beauty that it well-translates itself in a solid show.

Many fans watch this genre for the world-building and the concept of this anime.

It’s too popular. So, considering it, the below-mentioned will provide a list of the Isekai anime with op main characters, which for sure you will love to read and watch. 

Isekai Anime with OP MC ( Main Characters ) 2021

  • Ixion Saga DT
  • In Another World with my Smartphone
  • The Rising of the Shield Hero
  • How Not to Summon a Demon Lord
  • Sword Art Online
  • Magical Girl Madoka Magica
  • No Game No Life
  • Arifureta
  • The Devil is a Part-Timer
  • Log Horizon
  • Soul Land
  • Stigma Of The Wind
  • That Time I Got Reincarnated as a Slime
  • Seven Senses of the Re’Union
  • Chivalry Of A Failed Knight
  • Noragami
  • Marchen Awakens Romance
  • The Irregular At Magic High School

1. Ixion Saga DT

Ixion Saga DT

Herein, Kon Hokaze, the protagonist, found himself in a mysterious energy world named Alma.

In this Isekai anime with op mc, the mc then saves Ecarlate, the princess, without even knowing himself to be overpowered.

So, for him, he was just a regular guy who later joined the honor guard of the princess for fighting the militant faction which tried capturing her. 

The development of characters here is quite great, and it is one best op mc anime.

Apart from that, it is also fun to watch Kon grow as the op mc with all the action.

2. In Another World with my Smartphone

In Another World with my Smartphone

The story of this isekai anime with op mc is about Touya Mochizuki, who died because of God’s mistake.

He was then provided with another chance for living in the world, wherein he was given a smartphone that worked in the world.

This is how his journey began to continue in there with his brute strength and life that is quite like the video game with the cheat code.

If you feel unsure about this anime op mc, well, remember this might not be the one you might expect, but it does have some good share of the moments.

Therefore, it is to be called the best anime, which has the aspects of not just action and adventure but also romance, comedy, etc., and it will for sure not cease to impress you.

3. The Rising of the Shield Hero

The Rising of the Shield Hero

In here, Naofumi Iwatani gets summoned to another world with some of the other heroes for saving the world from the disasters.

As he was the shield hero, he gets underestimated and therefore betrayed by the kingdom’s princess.

The real story of this Isekai anime with op mc started when with no place to go, he left the place for becoming stronger and the legendary shield hero with incredible op abilities.

So, if one wishes to watch marvelous and action’s intensity, this is it.

This op mc Isekai anime, the journey of the op shield hero, will bring forward the amazing life-changing journey one would love to watch.

4. How Not to Summon a Demon Lord

How Not to Summon a Demon Lord

Fans who love the Isekai anime with op mc and especially ones with respect to the game world, their craze cannot truly be explained.

Even in this anime, the character is the gamer who soon finds himself in the world of video games, which was one of his favorites.

The harem herein is designed well with great personalities.

The protagonist herein was an avid player and overpowered in-game.

He later turned out to be lord Diablo, the demon. When the reversed situation worked, he ended up with 2 slave girls, a panther, and an elf.

It is then Diablo set out for helping them all with their mission and moving along in the adventure to free them.

The best is, Diablo is too overpowered to be stopped by anyone.

5. Sword Art Online

Sword Art Online

In this Isekai anime with op mc, players will see that this is a virtual MMORPG game that had nerve gear functioning.

It attracted players, and once many logged into it, they weren’t able to log out.

The only way to do that was to make sure to clear all of the game levels.

The catch here was, if they died in-game, they would be dealt with in real life.

This anime overpowered mc uses many elements in a quite surprising manner, and of course, the character was op as hell.

6. Magical Girl Madoka Magica

Magical Girl Madoka Magica

Any of the Isekai anime with op mc fans must have heard a lot of the series of the magical girl with one complicated plot.

Well, this is it, and herein the main character is Madoka Kaname.

She was one powerful girl who carried magic in order to exist within the entire series.

However, she did sacrifice herself at the end and became an all completely powerful being.

Which was strong enough for becoming law, and then alters the reality, trying to change the fates of all those magical girls for eternity.

7. No Game No Life

No Game No Life

Here, within this Isekai anime with op mc, is the story of the two siblings, Shiro and Sora, who were geniuses in gaming.

It was that one day when they got summoned to another world that is full of games, and they had the chance to challenge God.

The best part of this anime is that herein the animation is unique, and Madhouse Studio did its best.

One will love this anime for sure, with both the characters overpowered and with their brains not losing the fight at all.

8. Arifureta


In this anime where mc is op, the protagonist is Hajime Nagumo.

This animated Isekai is quite brilliant if we say.

In the story, one will see that Hajime gets insulted, humiliated, and ridiculed for his lack of powers, and later, he even gets betrayed by his classmate.

Well, in order to turn the situation, he becomes stronger and starts creating a weapon for escaping the dungeon.

He becomes insanely powerful who can easily destroy his enemies by destroying their organ to organs.

With his journey continuing, he then met some great characters in this Isekai anime with op mc, who added the best of colors to the story.

9. The Devil is a Part-Timer

The Devil is a Part-Timer

In here, one will find the devil living amidst men, and this makes the Isekai anime with op mc more and more powerful.

The devil, while conquering the new land, he gets intercepted by Emilia and then finds himself in the city of Tokyo, wherein is set this anime where mc is op.

The best part in here is that Sadao Maou, the devil lost all powers, but he had the power to regenerate, teleport, and some mind control abilities too.

He uses it all while it is revealed that Sadao’s and Emilia’s lives are intertwined.

These characters did unfold in quite a hilarious way; one will definitely love to watch what happened.

10. Log Horizon

Log Horizon, Isekai anime with op mc

Herein described is the story of Elder Tale, which is a popular online RPG.

One day many players in thousands get transported to the world, which resembled a game. 

Talking about the protagonist, he is quite smart and also overpowered in his way.

If one has loved watching another gaming concept Isekai anime with op mc, you will for sure love this too.

11. Soul Land

Soul Land

Tang San is a Tang Sect prodigy, but he was forced for jumping off Hell’s Peak, but this happened after he stole the secret teachings of the clan.

Later, he also got reincarnated to another world wherein there was no magic, but it surely had mystical souls.

For anyone who is in Chinese anime, for sure, you will love this Isekai anime with op mc.

If you do not love Chinese anime, well, Soul Land is a huge masterpiece.

Soul Land’s main character is fabulous, and it has a great story too.

The fantasy concept of it, it was a total of a new level which one might not have witnessed before.

12. Stigma Of The Wind

Stigma Of The Wind, Isekai anime with op mc

Herein this Isekai anime with op mc goes with the name of Kazuma Kannagi.

The character didn’t start off as overpowered.

When he was just 18, he got beaten badly by a 12-year-old female who was his second cousin while they continued to duel for Enraiha (sword for family’s heir). 

Kazuma comes from a family which is flame wielding, and he is inept with fire usage.

Later he was even banished from the family.

To make this story short, he, after 4 years, returned with the new name and power to control the wind.

It is then he became overpowered, and none were able to be in his way.

13. That Time I Got Reincarnated as a Slime

That Time I Got Reincarnated as a Slime

This anime is one of the popular Isekai anime with op mc.

Satoru Mikami is the protagonist herein who has been living an unhappy life.

He was stabbed by a stranger, and then he was reborn in another world that was full of magical users.

But he was born as the Slime with one ability of predator, which allowed him to absorb skills after he devoured the things.

The anime is quite thrilling and carries the excitement wherein the op mc further becomes allies with the dragon, who then renamed him as Rimuru Tempest.

It was later also seen that the op protagonist here also had to defend himself along with his allies from the demons and monsters who just wanted to destroy them.

14. Seven Senses of the Re’Union

Seven Senses of the Reunion, Isekai anime with op mc

This Isekai anime with op mc involves the MMORPG game.

Herein the op protagonist is Haruto Amou, who, amidst the 6 amazing players, is the best.

He is too powerful, and he can easily manipulate the defensive and offensive auras that exist inside him.

Even when he didn’t use the weapons, he still managed to win the battles and get appreciated for the qualities he had.

15. Chivalry Of A Failed Knight

Chivalry Of A Failed Knight

In the Elite Kurogane family, Ikki Kurogane is considered as not good for anything member.

He was called the worst one, but with time, his character became stronger in the Isekai anime with op mc.

He was even able to defeat the top A rank blaster, Stella Vermillion.

Ikki might lack the magical power, but his training, it pushed his body beyond limits, and it helped him increase his strength.

He also mastered as a swordsman.

Talking of the op mc anime, well, the romance in here is great.

The magic school and the harem, it was a bit overdone, though.

16. Noragami

Noragami, Isekai anime with op mc

It is one of the supernatural/action anime which has a female lead character.

Hiyori Iki is the protagonist herein who gets involved in the accident, and as a twist to her fate, the soul is not free to slip out of the body.

This is, of course, weird considering one person living 2 separate lives. 

The development allowed the Hiyori to have access to a world wherein resided the demons.

In regular anime, this homegirl made friends with God and the sword, which was in the form of the human soul.

The rest, its history, and the trio, well, they had lots and lots of adventure while they fought against the different entities.

For sure, this Isekai anime with op mc, it is a great watch if one pays attention to it.

17. Marchen Awakens Romance

Marchen Awakens Romance

This Isekai anime with op mc is awesome.

Herein the protagonist was physically weak and wasn’t able to see without glasses.

He thought he wished to be part of the fictional world, and one day his life changed when he got summoned to the world of his dreams.

Well, in this place, he was also overpowered and possessed the physical strength of superhuman and had some powerful magical weapons too.

A lot of mystery exists in this anime world, and we assure, you will be totally glued to the screen while op protagonist learns the harsh lessons.

18. The Irregular At Magic High School

The Irregular At Magic High School, Isekai anime with op mc

The anime in the high school herein has a magical ranking system, and we assure with the story going ahead, you will love this Isekai anime with op mc.

Herein the main characters are Tatsuya and Miyuki Shiba.

They were siblings, and amidst the two, Tatsuya lacked the magical attributes.

Tatsuya herein was overpowered mc in this anime who was smart, possessed knowledge, and had some combat abilities.

He also had decomposition magic, which put him even above magic users.

The rest, well, know by watching this great watch.

19. Ascendance of a Bookworm

Isekai anime with op mc

This isekai anime with op mc brings forward the story of the bookworm who finds a job at the library at one of the universities. However, she gets killed after some time as she graduates her college.

Then, she gets reborn as a soldier’s daughter, who was named Myne. She was born in a world wherein the literacy rate was very low and books, well, they were scarce. Even when she wanted to read, she wasn’t able to find many books around.

This is where she made it her goal to become a librarian and get access to unlimited books. But will she be able to do this? Watch to know more.

20. How to Summon a Demon Lord

How Not to Summon a Demon Lord

By all means, you will love the harem in here and the personalities which are well-designed. One will not be able to explain the love of Isekai for the game world.

Herein this anime, the character is a gamer, and he gets himself into the mysterious world, which turned to be his favorite game. As he was an avid player, the protagonist herein is the op, and he turned to be the Demon Lord named Diablo.

In the reverse situation, he also ended up with 2 slave girls, a panther, and one elf. Now his mission is to help the girls while the adventure of the gamer and the anime continues ahead.

21. Saga of Tanya the Evil

The Saga of Tanya the Evil

This anime’s existence is due to the man who didn’t believe in God. In the former life of Tanya, he got killed by the employee, and then God appeared in front of him. God questioned him about his lacking faith, and there was also an argument.

It continued till he got reincarnated in a young girl’s body named Loli, and she was in the middle of the ongoing war. Now how this isekai anime with op mc moves ahead is quite challenging, and for sure, one will enjoy watching it.

22. Overlord

Overlord anime where the main character is op

This is the dark isekai anime, which brings forward the protagonist named Ainz Ooal Gown, a veteran player who was trapped in the world of the game. He was there without any human emotions, and his powers were limitless.

In simple words, he was capable of beating down anyone with just one lift of the finger. So, for sure, you will enjoy watching this op mc who was exploring the world, trying to solve mysteries, and searching for answers. Believe it; it is fun.

23. Wise Man’s Grandchild

Wise Man’s Grandchild Season 2 Plot

This is one of the brilliant anime wherein the op mc Shin Wolford was the grandchild of the known magician (Merlin Wolford) of the world. This isekai anime with op mc will also take us to the shin’s former life wherein he was the young man who suddenly lost his life and got reincarnated within the magical world.

He then learned all of his grandpa’s teachings, and op herein is definitely an understatement. The knowledge Shin has of science from the previous world he was in help serve a lot within his magic journey of his as he was using the magical tools for revolutionalizing things. He used his words can also do magic spells.

What is Isekai Anime?

It is the anime that focuses more on the characters who get transported to another world, and they find it not easy to survive. They are always seen to be set out on some or the other mission or the quest.

The genre’s entire premise, allows the action, personal growth, fantastic animation, and introspection to be brought ahead. It is imaginative and full of loads and loads.

Final Words

It is to be noted that Isekai anime with op mc, in here the Isekais and the op, they go together.

Some even train like the crazies for becoming the overpowered kickass characters.

Hopefully, the list above of the Isekai anime with op mc will be able to provide you with a completely new experience and a lot of fun.

Hope you love it all and come looking for more. 

We assure with proper research; we will keep posting such lists to provide some unique suggestions which will be loved by you.

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